Are Mushrooms High In Histamine?

Mushrooms are a delicious and versatile ingredient found in many dishes around the world. But for those with histamine intolerance, consuming certain foods can cause unwanted symptoms. Are mushrooms one of those foods? In this article, we’ll explore whether mushrooms are high in histamine and what you can do to enjoy them without discomfort.

Histamine intolerance can be a frustrating and debilitating condition, causing symptoms like headaches, hives, and digestive issues. If you’re someone who loves mushrooms but experiences histamine-related symptoms after eating them, read on to learn more about the relationship between mushrooms and histamine.

are mushrooms high in histamine?

Are Mushrooms High in Histamine?

Mushrooms are a popular ingredient in various cuisines worldwide. They come in different shapes, sizes, and flavors, making them a versatile addition to any dish. However, some people may wonder if mushrooms are high in histamine, a chemical produced by the immune system that causes allergic reactions. In this article, we’ll explore whether mushrooms are high in histamine and their potential health benefits.

What is Histamine?

Histamine is a chemical produced by the immune system in response to allergens, injuries, and infections. It’s a neurotransmitter that regulates various bodily functions, including digestion, sleep, and immune response. Histamine triggers an inflammatory response to protect the body from foreign substances, such as bacteria, viruses, and toxins.

Symptoms of Histamine Intolerance

Some people may experience histamine intolerance, a condition where the body produces too much histamine or has difficulty breaking it down. Histamine intolerance can cause various symptoms, including:

  • Headaches and migraines
  • Nasal congestion and sinus problems
  • Hives, rashes, and itching
  • Digestive issues, such as bloating, diarrhea, and nausea
  • Anxiety and insomnia

What are Mushrooms?

Mushrooms are fungi that grow in the wild or cultivated environments. They’re low in calories and fat but rich in nutrients, such as fiber, protein, vitamins, and minerals. Mushrooms have been used for centuries in traditional medicine to treat various health conditions, such as cancer, diabetes, and immune disorders.

Are Mushrooms High in Histamine?

Mushrooms are not considered high in histamine compared to other foods, such as aged cheese, fermented products, and processed meats. However, mushrooms can contain small amounts of histamine, especially if they’re stored improperly or exposed to air for too long. Freshly picked mushrooms are less likely to contain histamine than older ones.

Factors that Affect Histamine Levels in Mushrooms

The following factors can affect the histamine levels in mushrooms:

  • Storage: Mushrooms should be stored in a cool, dry place, preferably in a paper bag or container with ventilation. Avoid storing mushrooms in plastic bags or tight containers as they can trap moisture and promote bacterial growth, which produces histamine.
  • Cooking: Cooking mushrooms can reduce their histamine content as heat breaks down the chemical. However, overcooking or frying mushrooms can increase their histamine levels as high temperatures can promote bacterial growth.
  • Species: Different mushroom species can have varying histamine levels depending on their growing conditions, harvesting time, and processing methods. For instance, shiitake mushrooms are considered high in histamine compared to button mushrooms.

Benefits of Mushrooms

Mushrooms have several potential health benefits due to their nutrient content and bioactive compounds. Some of the benefits include:

Source of Nutrients

Mushrooms are low in calories but rich in nutrients, such as fiber, protein, vitamins, and minerals. They’re an excellent source of vitamin D, which plays a crucial role in bone health, immune function, and mood regulation. Mushrooms also contain antioxidants, such as ergothioneine and glutathione, which protect the body from oxidative stress and inflammation.

Potential Anti-Cancer Properties

Mushrooms contain bioactive compounds, such as polysaccharides, beta-glucans, and triterpenoids, which have shown anti-cancer properties in preclinical studies. These compounds can modulate the immune system, inhibit tumor growth, and induce apoptosis (programmed cell death) in cancer cells. However, more research is needed to confirm their efficacy in humans.

May Improve Immune Function

Mushrooms contain beta-glucans, a type of polysaccharide that can stimulate the immune system and enhance its response to pathogens. Beta-glucans can activate white blood cells, such as macrophages and natural killer cells, and promote the production of cytokines, which regulate immune function. Some studies have suggested that beta-glucans may improve immune function in people with compromised immune systems, such as cancer patients.

Mushrooms Vs. Other Foods High in Histamine

Compared to other foods high in histamine, mushrooms are relatively low in histamine levels. Here are some of the common foods high in histamine:

Foods High in Histamine Reasons
Aged cheese Longer fermentation time
Fermented products Microbial fermentation
Processed meats Chemical additives and preservatives
Citrus fruits High levels of vitamin C
Shellfish High in histidine, a precursor to histamine

Conclusion

Mushrooms are a nutritious and flavorful ingredient in different dishes. While they can contain small amounts of histamine, they’re not considered high in histamine compared to other foods. Proper storage and cooking methods can reduce the histamine levels in mushrooms and enhance their health benefits. However, people with histamine intolerance should consult their healthcare provider before consuming mushrooms or any other food high in histamine.

Frequently Asked Questions

Here are some common questions related to the histamine content of mushrooms.

What is histamine?

Histamine is a chemical produced by the body as part of the immune response. It plays a role in inflammation and allergies, but can also cause symptoms such as itching, hives, and swelling.

Some foods are high in histamine or can trigger the body to release more histamine, which can cause symptoms in sensitive individuals.

Which mushrooms are high in histamine?

The histamine content of mushrooms can vary depending on the type and how they are prepared. In general, mushrooms are considered to be a low-histamine food and are usually well-tolerated by most people.

However, some people may be sensitive to certain types of mushrooms, such as shiitake or portobello, and experience symptoms such as headaches, hives, or digestive issues.

Can eating mushrooms cause a histamine reaction?

In rare cases, eating mushrooms can cause a histamine reaction in people who are sensitive to histamine or have a histamine intolerance. Symptoms may include itching, flushing, hives, or difficulty breathing.

If you experience these symptoms after eating mushrooms, it’s important to seek medical attention and avoid eating mushrooms in the future.

How can I reduce the histamine content of mushrooms?

There are several ways to reduce the histamine content of mushrooms, such as cooking them thoroughly, storing them properly, and choosing fresh mushrooms over older ones.

If you are sensitive to histamine or have a histamine intolerance, it’s important to talk to your doctor or a registered dietitian to develop a safe and healthy diet plan.

What are some low-histamine alternatives to mushrooms?

If you are looking for low-histamine alternatives to mushrooms, there are many options available, such as leafy greens, broccoli, cauliflower, zucchini, and other non-starchy vegetables.

You can also try incorporating more low-histamine proteins, such as chicken, turkey, fish, or tofu, into your diet to help meet your nutrient needs.

Histamine Intolerance SYMPTOMS (Watch Out for #3!)


In conclusion, mushrooms are not necessarily high in histamine. While some types of mushrooms may contain higher levels of histamine, the overall histamine content of mushrooms is relatively low. It is important to note that histamine intolerance is a complex condition that can vary from person to person. If you suspect that you have a histamine intolerance, it is recommended that you speak with a healthcare professional to determine the best course of action.

While mushrooms may not be a significant source of histamine, they do offer a variety of health benefits. Mushrooms are a good source of antioxidants, vitamins, and minerals, and they may help to boost immunity and reduce inflammation. Additionally, mushrooms are a versatile ingredient that can be added to many dishes, making them a great choice for anyone looking to add more nutrients to their diet.

Overall, while mushrooms may not be a significant source of histamine, they are still a nutritious and delicious food that can be enjoyed in a variety of ways. Whether you are looking to improve your health or simply enjoy the taste of mushrooms, there are many reasons to incorporate this versatile ingredient into your diet.